Linked Life Data

17520284

Source:http://linkedlifedata.com/resource/pubmed/id/17520284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-2-27
pubmed:abstractText
Pediatric inflammatory bowel disease (IBD) usually manifests in childhood or adolescence, but a small number of cases present in infancy. Genetic factors are more important than environmental ones in the onset of pediatric IBD. We report here the concurrent manifestation of IBD and familial Mediterranean fever (FMF) in three infants (less than 6 months of age) in whom infantile ulcerative colitis (UC) was associated with the MEFV mutation. One patient required colectomy before the diagnosis of FMF, and in the other two patients, the UC could not be controlled until colchicine was added to the drug regimen. We suggest that the onset of UC in infants should prompt a search for MEFV mutations as this association may influence the management of the disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0340-6199
pubmed:author
pubmed:issnType
Print
pubmed:volume
167
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
391-3
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The familial Mediterranean fever (MEFV) gene may be a modifier factor of inflammatory bowel disease in infancy.
pubmed:affiliation
Department of Pediatric Gastroenterology, Gazi University, Ankara, Turkey. drsinansari@yahoo.com
pubmed:publicationType
Journal Article, Case Reports