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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2007-5-23
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pubmed:abstractText |
c-Jun N-terminal kinase (JNK) is reported to play crucial roles in T-cell activation and differentiation, and SP600125 is a small molecule that inhibits JNK. The aim of this study was to examine immunosuppressive action of this compound.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
|
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pubmed:issn |
0041-1337
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1358-64
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17519787-Animals,
pubmed-meshheading:17519787-Anthracenes,
pubmed-meshheading:17519787-Enzyme Inhibitors,
pubmed-meshheading:17519787-Heart Transplantation,
pubmed-meshheading:17519787-Isoantigens,
pubmed-meshheading:17519787-JNK Mitogen-Activated Protein Kinases,
pubmed-meshheading:17519787-Lymph Nodes,
pubmed-meshheading:17519787-Lymphocyte Activation,
pubmed-meshheading:17519787-Male,
pubmed-meshheading:17519787-Rats,
pubmed-meshheading:17519787-Rats, Inbred BN,
pubmed-meshheading:17519787-Rats, Inbred Lew,
pubmed-meshheading:17519787-Transplantation, Homologous
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pubmed:year |
2007
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pubmed:articleTitle |
Suppression of alloreactivity and allograft rejection by SP600125, a small molecule inhibitor of c-Jun N-terminal kinase.
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pubmed:affiliation |
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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