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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-11
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pubmed:abstractText |
Total hip replacement can be complicated by periprosthetic osteolysis. Monocytes/macrophages play a major role in the formation of the foreign body granulomas induced by wear debris. We hypothesized that periprosthetic monocytes/macrophages do not only accelerate inflammatory and osteoclast-mediated osteolytic processes, but also resorb periprosthetic bone directly by themselves. This study was designed to evaluate the osteolytic potential in vitro of monocytes/macrophages derived from bone marrow.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1552-4973
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-204
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pubmed:meshHeading |
pubmed-meshheading:17514728-Acid Phosphatase,
pubmed-meshheading:17514728-Animals,
pubmed-meshheading:17514728-Bone Marrow Cells,
pubmed-meshheading:17514728-Bone Resorption,
pubmed-meshheading:17514728-Cell Adhesion,
pubmed-meshheading:17514728-Cells, Cultured,
pubmed-meshheading:17514728-Dentin,
pubmed-meshheading:17514728-Femur,
pubmed-meshheading:17514728-Immunohistochemistry,
pubmed-meshheading:17514728-Isoenzymes,
pubmed-meshheading:17514728-Macrophages,
pubmed-meshheading:17514728-Monocytes,
pubmed-meshheading:17514728-Osteolysis,
pubmed-meshheading:17514728-Phagocytosis,
pubmed-meshheading:17514728-Physical Stimulation,
pubmed-meshheading:17514728-Rats,
pubmed-meshheading:17514728-Rats, Wistar,
pubmed-meshheading:17514728-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17514728-Surface Properties
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pubmed:year |
2008
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pubmed:articleTitle |
Enhanced osteolytic potential of monocytes/macrophages derived from bone marrow after particle stimulation.
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pubmed:affiliation |
Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata 990-9585, Japan. ytamaki@med.id.yamagata-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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