Source:http://linkedlifedata.com/resource/pubmed/id/17514192
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-5-21
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pubmed:abstractText |
Lithium, an alkali metal, remains the gold-standard of the pharmacological treatment of bipolar disorder. Over the past decades, the potential of lithium to cause renal damage has been an issue of debate. Polyuria, polydipsia, and, to a lesser degree, nephrogenic diabetes insipidus are frequently observed under treatment with lithium. The glomerular filtration rate (GFR) decreases progressively in a smaller proportion of subjects after several years of treatment with lithium. An even smaller number of patients continue to develop renal insufficiency, ultimately leading to hemodialysis in a small minority of subjects exposed to lithium. So far, no tests exist to identify subjects at risk of lithium-induced nephropathy at an early stage. Therefore, regular monitoring of creatinine and creatinine clearance are recommended in all subjects taking lithium.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0048-5764
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
134-49
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:17514192-Adult,
pubmed-meshheading:17514192-Antimanic Agents,
pubmed-meshheading:17514192-Bipolar Disorder,
pubmed-meshheading:17514192-Creatine,
pubmed-meshheading:17514192-Diabetes Insipidus, Nephrogenic,
pubmed-meshheading:17514192-Dose-Response Relationship, Drug,
pubmed-meshheading:17514192-Female,
pubmed-meshheading:17514192-Glomerular Filtration Rate,
pubmed-meshheading:17514192-Humans,
pubmed-meshheading:17514192-Kidney Failure, Chronic,
pubmed-meshheading:17514192-Lithium Compounds,
pubmed-meshheading:17514192-Long-Term Care,
pubmed-meshheading:17514192-Male,
pubmed-meshheading:17514192-Recurrence,
pubmed-meshheading:17514192-Substance Withdrawal Syndrome
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pubmed:year |
2007
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pubmed:articleTitle |
Lithium-induced nephropathies.
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pubmed:affiliation |
Department of Psychiatry, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany. traedler@uke.uni-hamburg.de
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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