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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-7-27
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pubmed:abstractText |
Dilated cardiomyopathy (DCM) leads to dilation of the cardiac chambers and congestive heart failure. Recent reports have associated mutations in the SCN5A gene, which codes for the major cardiac sodium channel Nav1.5, with DCM. Although DCM is the most common form of cardiomyopathy, no animal studies have established this functional connection.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-6363
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pubmed:author |
pubmed-author:AllenFrances LFL,
pubmed-author:ClarkRobert BRB,
pubmed-author:CrossJames CJC,
pubmed-author:Geary-JooColleen T MCT,
pubmed-author:GilesWayne RWR,
pubmed-author:HesseMichaelM,
pubmed-author:KondoColleen SCS,
pubmed-author:KunnathuStanleyS,
pubmed-author:LinSuS,
pubmed-author:NygrenAndersA,
pubmed-author:SeversonDavid LDL
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
498-509
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pubmed:dateRevised |
2011-7-22
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pubmed:meshHeading |
pubmed-meshheading:17512504-Animals,
pubmed-meshheading:17512504-Bundle-Branch Block,
pubmed-meshheading:17512504-Cardiomyopathy, Dilated,
pubmed-meshheading:17512504-Echocardiography,
pubmed-meshheading:17512504-Electrocardiography,
pubmed-meshheading:17512504-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:17512504-Electrophysiology,
pubmed-meshheading:17512504-Gene Expression,
pubmed-meshheading:17512504-Genotype,
pubmed-meshheading:17512504-Mice,
pubmed-meshheading:17512504-Mice, Transgenic,
pubmed-meshheading:17512504-Models, Animal,
pubmed-meshheading:17512504-Muscle Proteins,
pubmed-meshheading:17512504-Myocytes, Cardiac,
pubmed-meshheading:17512504-Patch-Clamp Techniques,
pubmed-meshheading:17512504-Phenotype,
pubmed-meshheading:17512504-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17512504-Sodium Channels
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pubmed:year |
2007
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pubmed:articleTitle |
Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a.
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pubmed:affiliation |
Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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