Linked Life Data

17512419

Source:http://linkedlifedata.com/resource/pubmed/id/17512419

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10A
pubmed:dateCreated
2007-5-21
pubmed:abstractText
A distinct advantage of implantable device diagnostics is that the data may be made available on a continuous basis, rather than at sporadic intervals associated with clinical testing. Recently, intrathoracic impedance monitoring has also become available in some implantable devices as an index of congestion and thoracic fluid accumulation secondary to decompensated heart failure. Despite the potential advantages, new advances in implantable device diagnostic technology also pose important questions regarding their clinical application. To examine these questions and to generate hypotheses, the relation between daily intrathoracic impedance measurements and other physical measurements or comorbidities was studied. A retrospective review was performed of 25 patients who previously underwent implantation of a cardiac resynchronization therapy/defibrillator device with the capability to continuously monitor intrathoracic impedance. This limited scope analysis demonstrated that daily measurement of intrathoracic impedances might reveal the intrinsic relations between heart failure decompensation and the onset of atrial and ventricular arrhythmias. Abnormal patterns of intrathoracic impedance that has increased and plateaued after implant may indicate worsening heart failure. The severity of congestive heart failure at the time of interrogation may correlate with device-based impedance measurements. Weight, sex, and body index may have a limited impact on impedance, and the lowest impedances may be seen in older patients. Patients with severe pulmonary disease may present with unique daily impedance profiles. Finally, daily impedance may have unpredictable relations with other clinical markers of heart failure. In summary, intrathoracic impedance represents a clinically useful diagnostic tool that can increase our understanding of a dynamic disease state on an individual patient basis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
23G-8G
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Device monitoring of intrathoracic impedance: clinical observations from a patient registry.
pubmed:affiliation
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper University Hospital, Camden, New Jersey, USA. ja8pt@aol.com
pubmed:publicationType
Journal Article, Evaluation Studies