rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2007-6-26
|
pubmed:abstractText |
Neurocognitive dysfunction is an important source of patient morbidity and mortality after cardiac surgery that may disproportionately affect postmenopausal women. 17beta-Estradiol limits the extent of ischemic neuronal injury in a variety of experimental models. The purpose of this study was to evaluate whether perioperative administration of 17beta-estradiol to postmenopausal women reduces the frequency of neurocognitive dysfunction after cardiac surgery.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1524-4628
|
pubmed:author |
pubmed-author:BarzilaiBenicoB,
pubmed-author:BirgeStanleyS,
pubmed-author:Dávila-RománVictor GVG,
pubmed-author:DixonDavidD,
pubmed-author:FreedlandKennethK,
pubmed-author:FucetolaRobertR,
pubmed-author:HersheyTamaraT,
pubmed-author:HogueCharles WCWJr,
pubmed-author:NassiefAbullahA,
pubmed-author:SchechtmanKenneth BKB,
pubmed-author:ThomasBetsyB
|
pubmed:issnType |
Electronic
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2048-54
|
pubmed:dateRevised |
2011-2-21
|
pubmed:meshHeading |
pubmed-meshheading:17510454-Brain Ischemia,
pubmed-meshheading:17510454-Cardiac Surgical Procedures,
pubmed-meshheading:17510454-Cognition,
pubmed-meshheading:17510454-Cognition Disorders,
pubmed-meshheading:17510454-Estradiol,
pubmed-meshheading:17510454-Female,
pubmed-meshheading:17510454-Humans,
pubmed-meshheading:17510454-Intraoperative Complications,
pubmed-meshheading:17510454-Male,
pubmed-meshheading:17510454-Middle Aged,
pubmed-meshheading:17510454-Neuropsychological Tests,
pubmed-meshheading:17510454-Postmenopause,
pubmed-meshheading:17510454-Treatment Outcome
|
pubmed:year |
2007
|
pubmed:articleTitle |
Neurocognitive outcomes are not improved by 17beta-estradiol in postmenopausal women undergoing cardiac surgery.
|
pubmed:affiliation |
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA. chogue2@jhmi.edu
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, N.I.H., Extramural
|