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pubmed-article:17508776pubmed:dateCreated2007-5-18lld:pubmed
pubmed-article:17508776pubmed:abstractTextWe describe the packing features of the oligonucleotide duplex d(AAATTT)2, as determined by X-ray diffraction. There is little information on sequences that only contain A and T bases. The present structure confirms that these sequences tend to pack as a helical arrangement of stacked oligonucleotides in a B conformation with Watson-Crick hydrogen bonding. Our results demonstrate that the virtual TA base step between stacked duplexes has a negative twist that improves base stacking. This observation is consistent with the low stability of TA base steps in B-form DNA.lld:pubmed
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pubmed-article:17508776pubmed:authorpubmed-author:SubiranaJ AJAlld:pubmed
pubmed-article:17508776pubmed:authorpubmed-author:CamposJ LJLlld:pubmed
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pubmed-article:17508776pubmed:year2007lld:pubmed
pubmed-article:17508776pubmed:articleTitlePacking features of the all-AT oligonucleotide d(AAATTT).lld:pubmed
pubmed-article:17508776pubmed:affiliationDepartament d'Enginyeria Quimica, Universitat Politecnica de Catalunya, Av. Diagonal 647, E-08028 Barcelona, Spain.lld:pubmed
pubmed-article:17508776pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17508776pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed