Linked Life Data

17506219

Source:http://linkedlifedata.com/resource/pubmed/id/17506219

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1081
pubmed:dateCreated
2007-5-16
pubmed:abstractText
Intracellular microelectrode recordings have been made from probable motoneurons in the spinal cord of Xenopus laevis embryos during fictive 'swimming' in preparations paralysed with the neuromuscular blocking agent tubocurarine. These cells had resting potentials of -50 mV or more. During spontaneous or stimulus-evoked 'swimming' episodes: (a) the cells were tonically excited; the level of tonic synaptic excitation and the conductance increase underlying it were both inversely related to the 'swimming' cycle period; (b) the cells usually fired one spike per cycle in phase with the motor root burst on the same side; spikes did not overshoot zero and were evoked by phasic excitatory synaptic input on each cycle, superimposed on the tonic excitation; (c) in phase with motor root discharge on the opposite side of the body, the cells were hyperpolarized by a chloride-dependent inhibitory postsynaptic potential. The nature of synaptic potentials during 'swimming' was evaluated by means of intracellular current injections. The 'swimming' activity could be controlled by natural stimuli. The results provide clear evidence on the relation of tonic excitation to rhythmic locomotory pattern generation, and indirect evidence for reciprocal inhibitory coupling between antagonistic motor systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0962-8436
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
296
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-28
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Intracellular recordings from spinal neurons during 'swimming' in paralysed amphibian embryos.
pubmed:affiliation
Department of Zoology, University of Bristol, Bristol, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't