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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0205322,
umls-concept:C0205341,
umls-concept:C0332157,
umls-concept:C0599786,
umls-concept:C1367578,
umls-concept:C1444754,
umls-concept:C1514623,
umls-concept:C1516451,
umls-concept:C1521970,
umls-concept:C2745888,
umls-concept:C2756969
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pubmed:issue |
6
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pubmed:dateCreated |
2007-5-15
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pubmed:abstractText |
Exposure to persistent organohalogen pollutants was suggested to impair male reproductive function. A gene-environment interaction has been proposed. No genes modifying the effect of persistent organohalogen pollutants on reproductive organs have yet been identified. We aimed to investigate whether the CAG and GGN polymorphisms in the androgen receptor gene modify the effect of persistent organohalogen pollutant exposure on human sperm characteristics.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,4,5,2',4',5'-hexachlorobiphenyl,
http://linkedlifedata.com/resource/pubmed/chemical/AR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Dichlorodiphenyl Dichloroethylene,
http://linkedlifedata.com/resource/pubmed/chemical/Endocrine Disruptors,
http://linkedlifedata.com/resource/pubmed/chemical/Environmental Pollutants,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocarbons, Halogenated,
http://linkedlifedata.com/resource/pubmed/chemical/Polychlorinated Biphenyls,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Androgen
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1744-6872
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pubmed:author |
pubmed-author:BizzaroDavideD,
pubmed-author:BondeJens PeterJP,
pubmed-author:Bonefeld-JørgensenEva CEC,
pubmed-author:GiwercmanAleksanderA,
pubmed-author:GiwercmanCharlotteC,
pubmed-author:GiwercmanYvonne LundbergYL,
pubmed-author:INUENDO,
pubmed-author:JönssonBo A GBA,
pubmed-author:LesovoyVladimirV,
pubmed-author:LudwickiJan KJK,
pubmed-author:ManicardiGian-CarloGC,
pubmed-author:PedersenHenning SHS,
pubmed-author:Rignell-HydbomAnnaA,
pubmed-author:RylanderLarsL,
pubmed-author:SpanoMarcelloM,
pubmed-author:TiidoTarmoT,
pubmed-author:ToftGunnarG,
pubmed-author:ZvyezdayValentynaV
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
391-401
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pubmed:meshHeading |
pubmed-meshheading:17502831-Adult,
pubmed-meshheading:17502831-DNA Fragmentation,
pubmed-meshheading:17502831-Dichlorodiphenyl Dichloroethylene,
pubmed-meshheading:17502831-Endocrine Disruptors,
pubmed-meshheading:17502831-Environmental Exposure,
pubmed-meshheading:17502831-Environmental Pollutants,
pubmed-meshheading:17502831-Humans,
pubmed-meshheading:17502831-Hydrocarbons, Halogenated,
pubmed-meshheading:17502831-Male,
pubmed-meshheading:17502831-Minisatellite Repeats,
pubmed-meshheading:17502831-Pharmacogenetics,
pubmed-meshheading:17502831-Polychlorinated Biphenyls,
pubmed-meshheading:17502831-Polymorphism, Genetic,
pubmed-meshheading:17502831-Receptors, Androgen,
pubmed-meshheading:17502831-Semen,
pubmed-meshheading:17502831-Sperm Count,
pubmed-meshheading:17502831-Trinucleotide Repeats
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pubmed:year |
2007
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pubmed:articleTitle |
Androgen receptor gene CAG repeat length as a modifier of the association between persistent organohalogen pollutant exposure markers and semen characteristics.
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pubmed:affiliation |
Molecular Reproductive Medicine Research Unit, Department of Clinical Sciences, Reproductive Medicine Centre, Malmö University Hospital, Lund University, Malmö, Sweden. aleksander.giwercman@med.lu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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