rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2007-9-17
|
pubmed:abstractText |
The objective of this study was to characterize the rat monosodium iodoacetate (MIA)-induced model for osteoarthritis (OA) and determine the translatability of this model to human disease. This was accomplished through pathway, network and system level comparisons of transcriptional profiles generated from animal and human disease cartilage.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1063-4584
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1190-8
|
pubmed:meshHeading |
pubmed-meshheading:17500014-Animals,
pubmed-meshheading:17500014-Arthritis, Experimental,
pubmed-meshheading:17500014-Cartilage, Articular,
pubmed-meshheading:17500014-Disease Models, Animal,
pubmed-meshheading:17500014-Gene Expression Regulation,
pubmed-meshheading:17500014-Humans,
pubmed-meshheading:17500014-Iodoacetates,
pubmed-meshheading:17500014-Male,
pubmed-meshheading:17500014-Osteoarthritis,
pubmed-meshheading:17500014-Rats,
pubmed-meshheading:17500014-Rats, Wistar,
pubmed-meshheading:17500014-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17500014-Statistics as Topic,
pubmed-meshheading:17500014-Transcription, Genetic,
pubmed-meshheading:17500014-Transcription Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease.
|
pubmed:affiliation |
Molecular Pharmacology Group, Pfizer Global Research and Development, St. Louis, MO, USA.
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pubmed:publicationType |
Journal Article
|