Linked Life Data

17499485

Source:http://linkedlifedata.com/resource/pubmed/id/17499485

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-6-11
pubmed:abstractText
In the present study, event-related functional magnetic resonance imaging (fMRI) was used to examine the neural correlates of phobic fear by exposing spider phobic subjects to a visual presentation of spiders. In contrast to control subjects, spider phobics showed significantly increased activation in the amygdala and the pulvinar nucleus of the thalamus on the basis of region of interest (ROI) analysis. Furthermore, voxelwise analysis revealed increased activation related to phobia-specific pictures bilaterally in the anterior cingulate cortex, the left insular cortex and bilaterally in the supplementary motor area. These findings confirm the involvement of the amygdala in the processing of phobia-relevant stimuli as found earlier in a recent study. Moreover, the thalamus findings support the involvement of an extrageniculostriate pathway in the process of phobic fear.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0165-1781
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
155
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-20
pubmed:dateRevised
2008-4-17
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Visual presentation of phobic stimuli: amygdala activation via an extrageniculostriate pathway?
pubmed:affiliation
Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands.
pubmed:publicationType
Journal Article, Comparative Study