Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-11-9
pubmed:abstractText
Fertilization in hermaphroditic urochordates requires efficient mechanisms to prevent self-mating. By comparing gonadal transcripts of three genetically unrelated Ciona intestinalis individuals by suppression subtractive hybridization (SSH), we have previously identified a highly polymorphic gene coding for a transmembrane receptor which is expressed in follicle cells surrounding the mature oocyte [Kürn U, Sommer F, Hemmrich G, Bosch TCG, Khalturin K. Allorecogmition in urochordates: identification of a highly variable complement receptor-like protein expressed in follicle cells of Ciona. Dev Comp Immunol 2007; 31(4): 360-71]. Here, we show that in addition to follicle cells, oocytes also express variable genes. We have identified four novel Ciona genes coding for zona pellucida (ZP) domain proteins which are expressed in developing oocytes and which significantly vary among individuals. ZP containing proteins are thought to play a crucial and conserved role in controlling fertilization. Our results provide strong evidence that in Ciona components of both follicle cells and oocytes show a high degree of interindividual variability and, therefore, may take part in the prevention of self-mating as well as in the maintenance of species-specific fertilization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0145-305X
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1242-54
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
In the urochordate Ciona intestinalis zona pellucida domain proteins vary among individuals.
pubmed:affiliation
Zoological Institute, Christian-Albrechts-University of Kiel, Am Botanischen Garten 1-9, 24118 Kiel, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't