Linked Life Data

17497335

Source:http://linkedlifedata.com/resource/pubmed/id/17497335

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-5-14
pubmed:abstractText
Epidemiological, pathological and molecular studies indicate that subgroup J avian leukosis virus (ALV-J) infections are widely spread in "yellow chickens" of local breeds in China. ALV-J induced tumour mortality and the serological conversion rates to ALV-J were very high in some breeder flocks. Typical myelocytomatosis was demonstrated not only in livers, spleens, kidneys, and sternums, as in white meat-type chickens, but also in thymuses and the bursa of Fabricius. Especially, severe myeloid cell infiltration was found throughout the whole enlarged thymuses of some birds. ALV-J was isolated at high positive rates from both liver tumour samples and embryos collected from breeder flocks with tumours. At the same time, reticuloendotheliosis virus was also co-isolated with ALV-J in some tumour samples and embryos. Sequence analysis of env genes demonstrated that the gp85 and gp37 among six ALV-J isolates from "yellow chickens" of Chinese local breeds varied as highly as among ALV-J strains isolated from white meat-type chickens worldwide. But strain GD0512 isolated in 2005 from a "yellow chicken" farm in southern China had high identity of 95.1% for gp85 or 99.5% for gp37 to strain HN0001 isolated in 2000 from a white meat-type breeder farm in northern China, a much higher identity than to other yellow chicken and white chicken strains. This is the first report of the isolation and identification of ALV-J from yellow chickens of Chinese local breeds and also the first report of vertical co-infection of ALV-J and reticuloendotheliosis virus. The significance of co-infection of ALV-J and reticuloendotheliosis virus in pathogenesis is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0307-9457
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Epidemiological and pathological studies of subgroup J avian leukosis virus infections in Chinese local "yellow" chickens.
pubmed:affiliation
College of Veterinary Medicine, Shandong Agricultural University, Taian, Peoples Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't