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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-5-14
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pubmed:abstractText |
The zebrafish is an ideally suited vertebrate animal model for large-scale genetic screens and is emerging as a model organism in pharmacological and behavioral research. We investigated the effects of sedative hypnotics commonly used in humans on zebrafish locomotor activity and identified the corresponding genomic and receptor binding targets.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1744-6872
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
237-53
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17496723-Amino Acid Sequence,
pubmed-meshheading:17496723-Animals,
pubmed-meshheading:17496723-Baclofen,
pubmed-meshheading:17496723-Behavior, Animal,
pubmed-meshheading:17496723-Binding Sites,
pubmed-meshheading:17496723-Conserved Sequence,
pubmed-meshheading:17496723-Humans,
pubmed-meshheading:17496723-Hypnotics and Sedatives,
pubmed-meshheading:17496723-Larva,
pubmed-meshheading:17496723-Molecular Sequence Data,
pubmed-meshheading:17496723-Motor Activity,
pubmed-meshheading:17496723-Pharmacogenetics,
pubmed-meshheading:17496723-Phylogeny,
pubmed-meshheading:17496723-Radioligand Assay,
pubmed-meshheading:17496723-Receptors, GABA-A,
pubmed-meshheading:17496723-Receptors, GABA-B,
pubmed-meshheading:17496723-Receptors, Histamine H1,
pubmed-meshheading:17496723-Sequence Homology, Amino Acid,
pubmed-meshheading:17496723-Zebrafish
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pubmed:year |
2007
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pubmed:articleTitle |
Genomic and functional conservation of sedative-hypnotic targets in the zebrafish.
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pubmed:affiliation |
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, California, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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