Linked Life Data

17493916

Source:http://linkedlifedata.com/resource/pubmed/id/17493916

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-7-11
pubmed:abstractText
A person's ability to detect a weak visual target stimulus varies from one viewing to the next. We tested whether the trial-to-trial fluctuations of neural population activity in the human brain are related to the fluctuations of behavioral performance in a "yes-no" visual motion-detection task. We recorded neural population activity with whole head magnetoencephalography (MEG) while subjects searched for a weak coherent motion signal embedded in spatiotemporal noise. We found that, during motion viewing, MEG activity in the 12- to 24-Hz ("beta") frequency range is higher, on average, before correct behavioral choices than before errors and that it predicts correct choices on a trial-by-trial basis. This performance-predictive activity is not evident in the prestimulus baseline and builds up slowly after stimulus onset. Source reconstruction revealed that the performance-predictive activity is expressed in the posterior parietal and dorsolateral prefrontal cortices and, less strongly, in the visual motion-sensitive area MT+. The 12- to 24-Hz activity in these key stages of the human dorsal visual pathway is correlated with behavioral choice in both target-present and target-absent conditions. Importantly, in the absence of the target, 12- to 24-Hz activity tends to be higher before "no" choices ("correct rejects") than before "yes" choices ("false alarms"). It thus predicts the accuracy, and not the content, of subjects' upcoming perceptual reports. We conclude that beta band activity in the human dorsal visual pathway indexes, and potentially controls, the efficiency of neural computations underlying simple perceptual decisions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-3077
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
345-59
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Population activity in the human dorsal pathway predicts the accuracy of visual motion detection.
pubmed:affiliation
Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. tobias@cns.nyu.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't