| pubmed-article:17493597 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0017462 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0021792 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0379900 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C1413038 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0597879 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:17493597 | lifeskim:mentions | umls-concept:C1148454 | lld:lifeskim |
| pubmed-article:17493597 | pubmed:dateCreated | 2007-6-11 | lld:pubmed |
| pubmed-article:17493597 | pubmed:abstractText | Since the correlation between the serotonin (5-hydroxytryptamine, 5-HT) system and seizure activity remains to be clarified, we investigated the 5-HT system in the hippocampus of seizure-resistant (SR) and seizure-sensitive (SS) gerbils. There was no difference of the 5-HT system in the hippocampi of young animals (predisposed and juvenile gerbils) in both SR and SS gerbils. 5-HT immunoreactivity in the dorsal raphe nucleus and the median raphe nucleus was also similarly detected in both animal groups. As compared to SR adult gerbils, only 5-HT1A receptor immunoreactivity was selectively reduced in CA1 interneurons within SS adult gerbils. (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (a 5-HT1A receptor agonist, 1 and 2 mg/kg) markedly reduced paired-pulse inhibition in the CA1 region of SS adult gerbils only. These findings suggest that the selective reduction in 5-HT1A receptor expression on CA1 interneurons of SS adult gerbil may not be developmental defects, but be an acquired compensatory change induced by repeated seizure activity. | lld:pubmed |
| pubmed-article:17493597 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17493597 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17493597 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17493597 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17493597 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KwonOh-ShinOS | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KimJi-EunJE | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KimDae-WonDW | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:ChoiSoo-Young... | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KimDuk-SooDS | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KwakSung-EunS... | lld:pubmed |
| pubmed-article:17493597 | pubmed:author | pubmed-author:KangTae-ChonT... | lld:pubmed |
| pubmed-article:17493597 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17493597 | pubmed:day | 18 | lld:pubmed |
| pubmed-article:17493597 | pubmed:volume | 1154 | lld:pubmed |
| pubmed-article:17493597 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17493597 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17493597 | pubmed:pagination | 181-93 | lld:pubmed |
| pubmed-article:17493597 | pubmed:dateRevised | 2007-10-24 | lld:pubmed |
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| pubmed-article:17493597 | pubmed:meshHeading | pubmed-meshheading:17493597... | lld:pubmed |
| pubmed-article:17493597 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17493597 | pubmed:articleTitle | Seizure activity selectively reduces 5-HT1A receptor immunoreactivity in CA1 interneurons in the hippocampus of seizure-prone gerbils. | lld:pubmed |
| pubmed-article:17493597 | pubmed:affiliation | Department of Anatomy, College of Medicine, Hallym University, Chunchon 200-702, South Korea. | lld:pubmed |
| pubmed-article:17493597 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17493597 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17493597 | lld:pubmed |
