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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-5-11
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pubmed:abstractText |
One putative determinant of diabetic nephropathy is the Pro12Ala (P12A) polymorphism in the gene encoding peroxisome proliferator-activated receptor gamma (PPARgamma). Previous research has found a "protective" role for the A12 allele in association with type 2 diabetes, atherosclerosis, and measures of kidney damage. The objective of this study was to investigate a possible role for the P12A PPARgamma gene polymorphism with diabetic nephropathy in an isolated aboriginal Canadian population at high risk for renal disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1056-8727
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-71
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pubmed:meshHeading |
pubmed-meshheading:17493550-Age of Onset,
pubmed-meshheading:17493550-Alanine,
pubmed-meshheading:17493550-Amino Acid Substitution,
pubmed-meshheading:17493550-Blood Glucose,
pubmed-meshheading:17493550-DNA Primers,
pubmed-meshheading:17493550-Diabetes Mellitus, Type 2,
pubmed-meshheading:17493550-Diabetic Nephropathies,
pubmed-meshheading:17493550-Female,
pubmed-meshheading:17493550-Hemoglobin A, Glycosylated,
pubmed-meshheading:17493550-Humans,
pubmed-meshheading:17493550-Indians, North American,
pubmed-meshheading:17493550-Lipids,
pubmed-meshheading:17493550-Lipoproteins,
pubmed-meshheading:17493550-Male,
pubmed-meshheading:17493550-Middle Aged,
pubmed-meshheading:17493550-Ontario,
pubmed-meshheading:17493550-PPAR gamma,
pubmed-meshheading:17493550-Proline
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pubmed:articleTitle |
Peroxisome proliferator-activated receptor gamma polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes.
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pubmed:affiliation |
Robarts Research Institute, London, Ontario, Canada N6A 5K8.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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