Linked Life Data

17488676

Source:http://linkedlifedata.com/resource/pubmed/id/17488676

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-5-9
pubmed:abstractText
We here show that increased expression of MDM2, a negative regulator of p53, correlates with inferior survival in a series of 43 mantle cell lymphomas. MDM2 overexpression is associated with copy number gains of the MDM2 locus in single tumors, but not with the recently reported MDM2 promoter SNP309.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1592-8721
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
574-5
pubmed:meshHeading
pubmed-meshheading:17488676-Aged, pubmed-meshheading:17488676-DNA Damage, pubmed-meshheading:17488676-DNA Mutational Analysis, pubmed-meshheading:17488676-Female, pubmed-meshheading:17488676-Gene Dosage, pubmed-meshheading:17488676-Gene Duplication, pubmed-meshheading:17488676-Gene Expression Regulation, Neoplastic, pubmed-meshheading:17488676-Genes, p53, pubmed-meshheading:17488676-Humans, pubmed-meshheading:17488676-Lymphoma, Mantle-Cell, pubmed-meshheading:17488676-Male, pubmed-meshheading:17488676-Middle Aged, pubmed-meshheading:17488676-Neoplasm Proteins, pubmed-meshheading:17488676-Polymorphism, Single Nucleotide, pubmed-meshheading:17488676-Proportional Hazards Models, pubmed-meshheading:17488676-Proto-Oncogene Proteins c-mdm2, pubmed-meshheading:17488676-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:17488676-Survival Analysis
pubmed:year
2007
pubmed:articleTitle
Increased MDM2 expression is associated with inferior survival in mantle-cell lymphoma, but not related to the MDM2 SNP309.
pubmed:publicationType
Letter, Research Support, Non-U.S. Gov't