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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-5-9
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pubmed:abstractText |
Mantle cell lymphoma (MCL), a mature B-cell neoplasm, is genetically characterized by the translocation t(11;14)(q13;q32). However, secondary alterations are required for malignant transformation. The identification of inactivated tumor suppressor genes contributing to the development of MCL may lead to further elucidation of the biology of this disease and help to identify novel targets for therapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1592-8721
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pubmed:author |
pubmed-author:Callet-BauchuEvelyneE,
pubmed-author:EmuraMakitoM,
pubmed-author:GroenenPatriciaP,
pubmed-author:KamphuesKathrinK,
pubmed-author:LehmannUlrichU,
pubmed-author:RippergerTimT,
pubmed-author:RudolphCorneliaC,
pubmed-author:SchlegelbergerBrigitteB,
pubmed-author:SchradersMargitM,
pubmed-author:SkawranBrittaB,
pubmed-author:SteinemannDorisD,
pubmed-author:TauscherMarcelM,
pubmed-author:van KriekenJohan H J MJH,
pubmed-author:von NeuhoffNilsN
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pubmed:issnType |
Electronic
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
460-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17488656-Azacitidine,
pubmed-meshheading:17488656-Cell Line, Tumor,
pubmed-meshheading:17488656-Chromosomes, Human, Pair 1,
pubmed-meshheading:17488656-Chromosomes, Human, Pair 11,
pubmed-meshheading:17488656-Chromosomes, Human, Pair 14,
pubmed-meshheading:17488656-DNA, Neoplasm,
pubmed-meshheading:17488656-DNA Methylation,
pubmed-meshheading:17488656-Disease Progression,
pubmed-meshheading:17488656-GTPase-Activating Proteins,
pubmed-meshheading:17488656-Gene Expression Profiling,
pubmed-meshheading:17488656-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17488656-Gene Silencing,
pubmed-meshheading:17488656-Genes, Tumor Suppressor,
pubmed-meshheading:17488656-Humans,
pubmed-meshheading:17488656-Lymphoma, Mantle-Cell,
pubmed-meshheading:17488656-Neoplasm Proteins,
pubmed-meshheading:17488656-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17488656-Polymerase Chain Reaction,
pubmed-meshheading:17488656-Promoter Regions, Genetic,
pubmed-meshheading:17488656-Transcription, Genetic,
pubmed-meshheading:17488656-Translocation, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.
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pubmed:affiliation |
Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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