Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-5-7
pubmed:abstractText
Epstein-Barr virus (EBV) infection can be complicated by cholestatic jaundice and hemolytic anemia, although both complications rarely occur simultaneously. An 18-year-old female developed acute EBV infection complicated by cold agglutinin hemolysis and cholestasis. Corticosteroid and ursodeoxycholic acid were initiated but bilirubin peaked at 1297.47 micromol/L (75.7 mg/dL). Plasmapheresis was initiated and with the corticosteroids, resulted in resolution of extreme hyperbilirubinemia. The patient recovered rapidly, is healthy 2 years later and is neurologically intact. The early use of plasmapheresis with corticosteroids and ursodeoxycholic should be considered in EBV infections complicated by extreme hyperbilirubinemia to prevent the rare complication of adult-onset kernicterus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1077-4114
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-6
pubmed:dateRevised
2011-10-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Successful plasmapheresis for extreme hyperbilirubinemia caused by acute Epstein-Barr virus.
pubmed:affiliation
Department of Hematology/Oncology, Laboratory Medicine and Pathology, Children's Hospitals and Clinics of Minnesota, St Paul, MN 55102, USA.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't