Linked Life Data

17483710

Source:http://linkedlifedata.com/resource/pubmed/id/17483710

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-5-7
pubmed:abstractText
Oligodendroglioma is an uncommon childhood tumor and is more chemosensitive than other malignant glial neoplasms. Treatment involves gross total resection, and if anaplastic, radiation and chemotherapy. Distinct genetic alterations are associated with improved prognosis. We report a child with a low-grade oligodendroglioma that recurred as a high-grade oligodendroglioma and ultimately as extraneural systemic relapse. It was initially responsive to temozolomide, cyclophosphamide, etoposide, and carboplatin, perhaps predicted by combined loss of heterozygosity at 1p and 19q. This chemotherapy may be promising in treating malignant oligodendroglioma. However, he succumbed to progressive systemic disease. Positron emission spectroscopy scan was useful in sequentially assessing his disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1077-4114
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
319-22
pubmed:dateRevised
2011-10-6
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Extracranial relapse of an anaplastic oligodendroglioma in an adolescent: case report and review of the literature.
pubmed:affiliation
Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of Utah School of Medicine and Primary Children's Medical Center, Salt Lake City, Utah 84113, USA. carol.bruggers@ihc.com
pubmed:publicationType
Journal Article, Case Reports