17482523

Source:http://linkedlifedata.com/resource/pubmed/id/17482523

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008312, umls-concept:C0018591, umls-concept:C0752046, umls-concept:C1511636
pubmed:issue	6
pubmed:dateCreated	2007-6-4
pubmed:abstractText	Twin and family studies suggest that there is a significant heritable component to primary biliary cirrhosis (PBC). Selected cytotoxic T-lymphocyte-associated antigen-4 (CTLA4) gene polymorphisms have been proposed as nonspecific determinants of disease risk in a variety of autoimmune diseases, including PBC. However, there has been considerable debate over the validity of these associations and the precise location of the disease-promoting polymorphism.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101160775
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation, http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen, http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1542-7714
pubmed:author	pubmed-author:BaragiottaAnnaA, pubmed-author:BassendineMargaretM, pubmed-author:DonaldsonPeterP, pubmed-author:FloreaniAnnarosaA, pubmed-author:JamesOliverO, pubmed-author:JonesDavidD, pubmed-author:NewtonJuliaJ, pubmed-author:PearceSimonS, pubmed-author:TaylorJohnJ, pubmed-author:VeeramaniSivakumarS, pubmed-author:VenturiCarlaC, pubmed-author:WilsonValerieV
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	755-60
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:17482523-Adolescent, pubmed-meshheading:17482523-Adult, pubmed-meshheading:17482523-Aged, pubmed-meshheading:17482523-Antigens, CD, pubmed-meshheading:17482523-Antigens, Differentiation, pubmed-meshheading:17482523-CTLA-4 Antigen, pubmed-meshheading:17482523-Disease Progression, pubmed-meshheading:17482523-European Continental Ancestry Group, pubmed-meshheading:17482523-Female, pubmed-meshheading:17482523-Genetic Predisposition to Disease, pubmed-meshheading:17482523-Genotype, pubmed-meshheading:17482523-Great Britain, pubmed-meshheading:17482523-Haplotypes, pubmed-meshheading:17482523-Humans, pubmed-meshheading:17482523-Italy, pubmed-meshheading:17482523-Liver Cirrhosis, Biliary, pubmed-meshheading:17482523-Male, pubmed-meshheading:17482523-Middle Aged, pubmed-meshheading:17482523-Nucleic Acid Amplification Techniques, pubmed-meshheading:17482523-Polymorphism, Single Nucleotide, pubmed-meshheading:17482523-Seroepidemiologic Studies
pubmed:year	2007
pubmed:articleTitle	Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis.
pubmed:affiliation	Centre for Liver Research, School of Clinical Medical Sciences, The Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, United Kingdom. p.t.donaldson@ncl.ac.uk
pubmed:publicationType	Journal Article