Linked Life Data

17479726

Source:http://linkedlifedata.com/resource/pubmed/id/17479726

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-5-7
pubmed:abstractText
Sporadic inclusion body myositis (S-IBM) is a progressive, acquired myopathic process of unknown etiology. No known, successful or proven treatment exists. Quantitative EMG studies including concentric needle motor unit action potentials, interference pattern, macro-EMG and fiber density have allowed different measures to be made of the motor unit. These different measures allow inferences to be made in how the muscle fibers are distributed within both the normal and diseased motor unit. The present study is an effort to use multiple quantitative EMG measurements from the biceps brachii on a serial basis in order to study chronic changes in the motor unit with disease progression. Twenty-eight studies from 9 patients over a four-year period are shown. We conclude that while the concentric needle electrode is most helpful for diagnosing abnormality, the less selective macro-EMG and surface electrodes are better suited to monitor disease progression, especially in very weak muscles. These observations have practical applications for monitoring disease progression, or conversely, response to treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-150X
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-104
pubmed:meshHeading
pubmed:articleTitle
Serial quantitative electrophysiologic studies in sporadic inclusion body myositis.
pubmed:affiliation
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.