Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-5-17
pubmed:abstractText
Within a population of genetically identical cells there can be significant variation, or noise, in gene expression. Yet even with this inherent variability, cells function reliably. This review focuses on our understanding of noise at the level of both single genes and genetic regulatory networks, emphasizing comparisons between theoretical models and experimental results whenever possible. To highlight the importance of noise, we particularly emphasize examples in which a stochastic description of gene expression leads to a qualitatively different outcome than a deterministic one.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1056-8700
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-34
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Living with noisy genes: how cells function reliably with inherent variability in gene expression.
pubmed:affiliation
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. narendra@mit.edu
pubmed:publicationType
Journal Article, Review