rdf:type |
|
lifeskim:mentions |
umls-concept:C0009429,
umls-concept:C0018787,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035015,
umls-concept:C0085149,
umls-concept:C0205178,
umls-concept:C0450127,
umls-concept:C0556895,
umls-concept:C1280500,
umls-concept:C1548437,
umls-concept:C1708528,
umls-concept:C1882923
|
pubmed:issue |
4
|
pubmed:dateCreated |
2007-5-22
|
pubmed:abstractText |
Baohuoside-1 (B-1), a recently introduced novel immunosuppressant that was proved to be potent in inhibition of T and B cell proliferation and B-1, also prevents cardiac allograft rejection in rodents. The present study further proved that monotherapy of B-1's analogue B-1 aglycone effectively prolongs cardiac allograft survival and combination therapy of B-1 aglycone with tacrolimus (FK506) produces synergistic effect in prevention acute cardiac allograft rejection in the rat. .
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0738-1085
|
pubmed:author |
pubmed-author:ButkoD IuDIu,
pubmed-author:ChenHuifangH,
pubmed-author:DalozePierreP,
pubmed-author:JiangHongsiH,
pubmed-author:LinGengG,
pubmed-author:LiuLongshanL,
pubmed-author:QiShijieS,
pubmed-author:TamuraKouichiK,
pubmed-author:WangXiangX,
pubmed-author:XuDashengD,
pubmed-author:ZhaoHongH
|
pubmed:issnType |
Print
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
268-70
|
pubmed:meshHeading |
pubmed-meshheading:17477431-Acute Disease,
pubmed-meshheading:17477431-Animals,
pubmed-meshheading:17477431-Drug Therapy, Combination,
pubmed-meshheading:17477431-Flavonoids,
pubmed-meshheading:17477431-Graft Rejection,
pubmed-meshheading:17477431-Heart Transplantation,
pubmed-meshheading:17477431-Immunosuppressive Agents,
pubmed-meshheading:17477431-Male,
pubmed-meshheading:17477431-Random Allocation,
pubmed-meshheading:17477431-Rats,
pubmed-meshheading:17477431-Rats, Inbred BN,
pubmed-meshheading:17477431-Rats, Inbred Lew,
pubmed-meshheading:17477431-Survival Rate,
pubmed-meshheading:17477431-Tacrolimus,
pubmed-meshheading:17477431-Transplantation, Homologous
|
pubmed:year |
2007
|
pubmed:articleTitle |
Effect of Baohuoside-1 aglycone and tacrolimus monotherapy and combination therapy on prevention of acute heart allograft rejection in the rat.
|
pubmed:affiliation |
Laboratory of Experimental Surgery, Research Center of Centre Hospitalier de l'Université de Montréal, Hôspital Notre-Dame, Montreal, QC, Canada.
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pubmed:publicationType |
Journal Article
|