rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-5-22
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pubmed:abstractText |
Islet transplantation is an alternative to whole pancreas transplantation in curative therapy of diabetics. The outcome of engraftment of islet, however, remains disappointing. Rapid and adequate islet revascularization is crucial for the survival and function of transplanted islets. In this study, hepatic stellate cells (HSC) were cotransplanted with islet allografts, achieving marked prolongation of islet allografts. This was associated with enhanced revascularization within islet grafts as determined by anti-CD31 antibody staining.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0738-1085
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright (c) 2007 Wiley-Liss, Inc. Microsurgery 2007.
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pubmed:issnType |
Print
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pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
324-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17477430-Animals,
pubmed-meshheading:17477430-Antigens, CD31,
pubmed-meshheading:17477430-Endothelial Cells,
pubmed-meshheading:17477430-Graft Survival,
pubmed-meshheading:17477430-Hepatocytes,
pubmed-meshheading:17477430-Immunohistochemistry,
pubmed-meshheading:17477430-Insulin,
pubmed-meshheading:17477430-Islets of Langerhans,
pubmed-meshheading:17477430-Islets of Langerhans Transplantation,
pubmed-meshheading:17477430-Male,
pubmed-meshheading:17477430-Mice,
pubmed-meshheading:17477430-Mice, Inbred BALB C,
pubmed-meshheading:17477430-Mice, Inbred C57BL,
pubmed-meshheading:17477430-Transplantation, Homologous
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pubmed:year |
2007
|
pubmed:articleTitle |
Cotransplanted hepatic stellate cells enhance vascularization of islet allografts.
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pubmed:affiliation |
Department of Immunology, Cleveland Clinic, Cleveland, OH 44195, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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