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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-5-3
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pubmed:abstractText |
Repopulation of clonogenic tumor cells is inversely correlated with radiation treatment outcome in head and neck squamous cell carcinomas. A functional imaging tool to assess the proliferative activity of tumors could improve patient selection for treatment modifications and could be used for evaluation of early treatment response. The PET tracer 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) can image tumor cell proliferation before and during radiotherapy, and it may provide biologic tumor information useful in radiotherapy planning. In the present study, the value of (18)F-FLT PET in determining the lymph node status in squamous cell carcinoma of the head and neck was assessed, with pathology as the gold standard.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
726-35
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pubmed:meshHeading |
pubmed-meshheading:17475960-Adult,
pubmed-meshheading:17475960-Aged,
pubmed-meshheading:17475960-Aged, 80 and over,
pubmed-meshheading:17475960-Diagnosis, Differential,
pubmed-meshheading:17475960-Dideoxynucleosides,
pubmed-meshheading:17475960-Female,
pubmed-meshheading:17475960-Head and Neck Neoplasms,
pubmed-meshheading:17475960-Humans,
pubmed-meshheading:17475960-Lymph Node Excision,
pubmed-meshheading:17475960-Lymph Nodes,
pubmed-meshheading:17475960-Lymphatic Metastasis,
pubmed-meshheading:17475960-Male,
pubmed-meshheading:17475960-Middle Aged,
pubmed-meshheading:17475960-Neoplasm Recurrence, Local,
pubmed-meshheading:17475960-Positron-Emission Tomography,
pubmed-meshheading:17475960-Prognosis,
pubmed-meshheading:17475960-Pseudolymphoma,
pubmed-meshheading:17475960-Radiopharmaceuticals,
pubmed-meshheading:17475960-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
18F-FLT PET does not discriminate between reactive and metastatic lymph nodes in primary head and neck cancer patients.
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pubmed:affiliation |
Department of Radiation Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. e.troost@rther.umcn.nl
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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