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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-6-8
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pubmed:abstractText |
Sprague Dawley (SD) rats are significantly more sensitive than Long Evans (LE) rats to the disruption of prepulse inhibition (PPI) by systemically-administered dopamine (DA) agonists. This strain difference is heritable and insensitive to cross-fostering. Inherited differences in the ability of elevated DA activity to disrupt PPI may be useful for understanding the neural basis for PPI deficits in schizophrenia and other neuropsychiatric disorders.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-10958115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11007721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11103873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-1153628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11549216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11549223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11549226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-11713612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-12115851,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-12148935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-12655308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-12714174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-12759127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-1410139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-14751457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-15114433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-15263907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-15300358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-15300359,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-16010540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-16123742,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-16176381,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-17135482,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-693742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-7816867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-8539324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-8813362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-8931016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17475315-9715813
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0091-3057
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-10
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pubmed:dateRevised |
2011-9-15
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pubmed:meshHeading |
pubmed-meshheading:17475315-Amphetamine,
pubmed-meshheading:17475315-Animals,
pubmed-meshheading:17475315-Central Nervous System Stimulants,
pubmed-meshheading:17475315-Dopamine,
pubmed-meshheading:17475315-Dose-Response Relationship, Drug,
pubmed-meshheading:17475315-Female,
pubmed-meshheading:17475315-Injections, Subcutaneous,
pubmed-meshheading:17475315-Male,
pubmed-meshheading:17475315-Microinjections,
pubmed-meshheading:17475315-Nucleus Accumbens,
pubmed-meshheading:17475315-Pregnancy,
pubmed-meshheading:17475315-Rats,
pubmed-meshheading:17475315-Rats, Long-Evans,
pubmed-meshheading:17475315-Rats, Sprague-Dawley,
pubmed-meshheading:17475315-Species Specificity,
pubmed-meshheading:17475315-Startle Reaction
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pubmed:year |
2007
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pubmed:articleTitle |
Strain differences in the disruption of prepulse inhibition of startle after systemic and intra-accumbens amphetamine administration.
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pubmed:affiliation |
Department of Psychiatry, UCSD School of Medicine, La Jolla, CA 92093-0804, USA. nswerdlow@ucsd.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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