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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2007-7-9
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pubmed:abstractText |
A genome-wide bivariate analysis was conducted for body fat mass (BFM) and bone mineral density (BMD) in a large Caucasian sample. We found some quantitative trait loci shared by BFM and BMD in the total sample and the gender-specific subgroups, and quantitative trait loci with potential pleiotropy were disclosed. BFM and BMD, as the respective measure for obesity and osteoporosis, are phenotypically and genetically correlated. However, specific genomic regions accounting for their genetic correlation are unknown.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0021-972X
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pubmed:author |
pubmed-author:DengFei-YanFY,
pubmed-author:DengHong-WenHW,
pubmed-author:DengHong-YiHY,
pubmed-author:LeiShu-FengSF,
pubmed-author:ReckerRobert RRR,
pubmed-author:ShenHuiH,
pubmed-author:TanLi-JunLJ,
pubmed-author:TangZi-HuiZH,
pubmed-author:XiaoPengP,
pubmed-author:XiongDong-HaiDH,
pubmed-author:ZhaoLan-JuanLJ
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2751-7
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17473065-Adult,
pubmed-meshheading:17473065-Aged,
pubmed-meshheading:17473065-Aged, 80 and over,
pubmed-meshheading:17473065-Female,
pubmed-meshheading:17473065-Genome, Human,
pubmed-meshheading:17473065-Genomics,
pubmed-meshheading:17473065-Genotype,
pubmed-meshheading:17473065-Humans,
pubmed-meshheading:17473065-Lod Score,
pubmed-meshheading:17473065-Male,
pubmed-meshheading:17473065-Middle Aged,
pubmed-meshheading:17473065-Obesity,
pubmed-meshheading:17473065-Osteoporosis,
pubmed-meshheading:17473065-Quantitative Trait Loci,
pubmed-meshheading:17473065-Sex Factors
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pubmed:year |
2007
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pubmed:articleTitle |
A bivariate whole-genome linkage scan suggests several shared genomic regions for obesity and osteoporosis.
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pubmed:affiliation |
Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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