Linked Life Data

17470516

Source:http://linkedlifedata.com/resource/pubmed/id/17470516

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-5-1
pubmed:abstractText
This study investigated the acute effects of exercise on the postprandial levels of appetite-related hormones and metabolites, energy intake (EI) and subjective measures of appetite. Ghrelin, polypeptide YY (PYY), glucagon-like peptide-1 (GLP-1) and pancreatic polypeptide (PP) were measured in the fasting state and postprandially in 12 healthy, normal-weight volunteers (six males and six females) using a randomised crossover design. One hour after a standardised breakfast, subjects either cycled for 60 min at 65% of their maximal heart rate or rested. Subjective appetite was assessed throughout the study using visual analogue scales and subsequent EI at a buffet meal was measured at the end (3-h post-breakfast and 1-h post-exercise). Exercise significantly increased mean PYY, GLP-1 and PP levels, and this effect was maintained during the post-exercise period for GLP-1 and PP. No significant effect of exercise was observed on postprandial levels of ghrelin. During the exercise period, hunger scores were significantly decreased; however, this effect disappeared in the post-exercise period. Exercise significantly increased subsequent absolute EI, but produced a significant decrease in relative EI after accounting for the energy expended during exercise. Hunger scores and PYY, GLP-1 and PP levels showed an inverse temporal pattern during the 1-h exercise/control intervention. In conclusion, acute exercise, of moderate intensity, temporarily decreased hunger sensations and was able to produce a short-term negative energy balance. This impact on appetite and subsequent energy homeostasis was not explained by changes in postprandial levels of ghrelin; however, 'exercise-induced anorexia' may potentially be linked to increased PYY, GLP-1 and PP levels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-0795
pubmed:author
pubmed:issnType
Print
pubmed:volume
193
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
251-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:17470516-Adult, pubmed-meshheading:17470516-Analysis of Variance, pubmed-meshheading:17470516-Appetite, pubmed-meshheading:17470516-Blood Glucose, pubmed-meshheading:17470516-Cross-Over Studies, pubmed-meshheading:17470516-Energy Intake, pubmed-meshheading:17470516-Energy Metabolism, pubmed-meshheading:17470516-Exercise, pubmed-meshheading:17470516-Fasting, pubmed-meshheading:17470516-Fatty Acids, Nonesterified, pubmed-meshheading:17470516-Female, pubmed-meshheading:17470516-Gastrointestinal Hormones, pubmed-meshheading:17470516-Ghrelin, pubmed-meshheading:17470516-Glucagon-Like Peptide 1, pubmed-meshheading:17470516-Humans, pubmed-meshheading:17470516-Hunger, pubmed-meshheading:17470516-Male, pubmed-meshheading:17470516-Pancreatic Polypeptide, pubmed-meshheading:17470516-Peptide Hormones, pubmed-meshheading:17470516-Peptide YY, pubmed-meshheading:17470516-Postprandial Period, pubmed-meshheading:17470516-Triglycerides
pubmed:year
2007
pubmed:articleTitle
Effects of exercise on gut peptides, energy intake and appetite.
pubmed:affiliation
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, UK.
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't