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pubmed:abstractText |
Cardiovascular disease is a major cause of morbidity and mortality in individuals with type 1 diabetes. Resting heart rate (RHR) is a risk factor for cardiovascular disease in the general population, and case-control studies have reported a higher RHR in individuals with type 1 diabetes. In individuals with type 1 diabetes, there is a positive correlation between A1C and RHR; however, no prospective studies have examined whether a causal relationship exists between A1C and RHR. We hypothesized that intensive diabetes treatment aimed to achieve normal A1C levels has an effect on RHR in individuals with type 1 diabetes.
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pubmed:affiliation |
Program in Genetics and Genomic Biology, The Hospital for Sick Children, TMDT Building East Tower, Room 15-707, 101 College St., Toronto, ON M5G 1L7, Canada. andrew.paterson@utoronto.ca
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