Source:http://linkedlifedata.com/resource/pubmed/id/17467843
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-10-1
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pubmed:abstractText |
Type 2 diabetes (T2DM) is characterized by increased proinsulin-to-insulin ratio (P/I ratio), increased glycation and oxidative stress, and beta-cell dysfunction. Previous reports implicated that increased P/I ratio, glycation and oxidative stress constitute markers of beta-cell dysfunction in T2DM. However, its clinical relevance remains to be elucidated. Therefore, in the present study we investigated the relationship between the P/I ratio, glycation and oxidative stress markers in patients with T2DM, using newly developed intact chemiluminescent immunoassay for proinsulin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0168-8227
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
182-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17467843-Aged,
pubmed-meshheading:17467843-Diabetes Mellitus, Type 2,
pubmed-meshheading:17467843-Female,
pubmed-meshheading:17467843-Glycosylation End Products, Advanced,
pubmed-meshheading:17467843-Homeostasis,
pubmed-meshheading:17467843-Humans,
pubmed-meshheading:17467843-Insulin,
pubmed-meshheading:17467843-Male,
pubmed-meshheading:17467843-Middle Aged,
pubmed-meshheading:17467843-Oxidative Stress,
pubmed-meshheading:17467843-Proinsulin
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pubmed:year |
2007
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pubmed:articleTitle |
Relationship between proinsulin-to-insulin ratio and advanced glycation endproducts in Japanese type 2 diabetic subjects.
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pubmed:affiliation |
Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
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pubmed:publicationType |
Journal Article
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