| pubmed-article:17462831 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0237868 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C1858460 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C2350572 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0036679 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0599946 | lld:lifeskim |
| pubmed-article:17462831 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:17462831 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:17462831 | pubmed:dateCreated | 2007-5-22 | lld:pubmed |
| pubmed-article:17462831 | pubmed:abstractText | A previous study found that intracerebroventricular (ICV) infusion of 25 microg of alpha-MSH reduced the passive responses (crouched stance, eye-closing, piloerection) of guinea pig pups during a 3-h isolation in a novel environment. Because alpha-MSH has broad anti-inflammatory properties, the results suggested that proinflammatory factors play a role in mediating the behavior of isolated infants. The present study further investigated this possibility. In Experiment 1, injection of lipopolysacchride (LPS) increased the number of 60-s intervals in which pups expressed the same three responses during a 1-h test, and ICV infusion of alpha-MSH significantly reduced the effect of LPS on crouching and piloerection. In Experiment 2, the prostaglandin synthesis inhibitor indomethacin (10 mg/kg) reduced the number of 60-s intervals in which pups exhibited both crouching and the full suite of passive responses during a 3-h isolation in a novel environment. Together these results provide further support for the hypothesis that the passive behaviors exhibited during prolonged isolation are "stress-induced sickness behaviors" mediated by proinflammatory factors. | lld:pubmed |
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| pubmed-article:17462831 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:17462831 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17462831 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17462831 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17462831 | pubmed:issn | 0306-4530 | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:DeakTerrenceT | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:HennessyMicha... | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:MakenDeborah... | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:Schiml-WebbPa... | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:BullingerKati... | lld:pubmed |
| pubmed-article:17462831 | pubmed:author | pubmed-author:MillerEmily... | lld:pubmed |
| pubmed-article:17462831 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17462831 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:17462831 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17462831 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17462831 | pubmed:pagination | 508-15 | lld:pubmed |
| pubmed-article:17462831 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:17462831 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17462831 | pubmed:articleTitle | Anti-inflammatory agents attenuate the passive responses of guinea pig pups: evidence for stress-induced sickness behavior during maternal separation. | lld:pubmed |
| pubmed-article:17462831 | pubmed:affiliation | Department of Psychology, Wright State University, Dayton, OH 45435, USA. michael.hennessy@wright.edu | lld:pubmed |
| pubmed-article:17462831 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17462831 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17462831 | lld:pubmed |
