Linked Life Data

1746196

Source:http://linkedlifedata.com/resource/pubmed/id/1746196

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
1992-1-16
pubmed:abstractText
Using a sensitive HPLC method, plasma concentrations of vitamin A and metabolites were measured from 6 female volunteers who had taken once daily 0.46 mg/kg BW retinol palmitate (Vitadral) for 10 days. The metabolites all-trans- and 13-cis-retinoic acid were increased significantly (2- and 5-fold, resp.) 6 h after the ist intake. 13-cis-4-oxo retinoic acid the 10th intake in the morning of the 10th day (9.22 +/- 2.77 ng/ml, 4-fold increase). The results show continuous increase of retinoic acids, which have to be considered as potential teratogens, after administration of vitamin A. The plasma concentration of retinol itself did not change, whereas only short-term increases were observed for retinol esters.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0044-4197
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1100-6
pubmed:dateRevised
2008-2-11
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Plasma level and metabolism of vitamin A (Vitadral) in women of reproductive age].
pubmed:affiliation
Klinik für Frauenheilkunde und Geburtshilfe, Friedrich-Schiller-Universität Jena, Bundesrepublik Deutschland.
pubmed:publicationType
Journal Article, English Abstract