17460549

Source:http://linkedlifedata.com/resource/pubmed/id/17460549

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003289, umls-concept:C0011570, umls-concept:C0205145, umls-concept:C0887848, umls-concept:C1882417
pubmed:issue	3
pubmed:dateCreated	2007-4-26
pubmed:abstractText	Recent evidence suggests that signalling cascades located downstream of monoamine receptors are altered following antidepressant treatment. Our objective was to investigate whether genetic polymorphisms in genes involved in these signalling cascades influenced antidepressant efficacy.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101231005
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antidepressive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Brain-Derived Neurotrophic Factor, http://linkedlifedata.com/resource/pubmed/chemical/CREB-Binding Protein, http://linkedlifedata.com/resource/pubmed/chemical/CREB1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CREBBP protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP Response..., http://linkedlifedata.com/resource/pubmed/chemical/G-protein beta3 subunit, http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Protein beta Subunits, http://linkedlifedata.com/resource/pubmed/chemical/Heterotrimeric GTP-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/RNA Splice Sites
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1744-6872
pubmed:author	pubmed-author:BlackwoodDouglasD, pubmed-author:DayRichard KRK, pubmed-author:MatthewsKeithK, pubmed-author:ReidIan CIC, pubmed-author:SmithDanielD, pubmed-author:SmithGillianG, pubmed-author:WilkieMurray J VMJ, pubmed-author:WolfCharles RolandCR
pubmed:issnType	Print
pubmed:volume	17
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	207-15
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17460549-Adolescent, pubmed-meshheading:17460549-Adult, pubmed-meshheading:17460549-Aged, pubmed-meshheading:17460549-Antidepressive Agents, pubmed-meshheading:17460549-Brain-Derived Neurotrophic Factor, pubmed-meshheading:17460549-CREB-Binding Protein, pubmed-meshheading:17460549-Cyclic AMP Response Element-Binding Protein, pubmed-meshheading:17460549-Depression, pubmed-meshheading:17460549-Female, pubmed-meshheading:17460549-GTP-Binding Protein beta Subunits, pubmed-meshheading:17460549-Genotype, pubmed-meshheading:17460549-Heterotrimeric GTP-Binding Proteins, pubmed-meshheading:17460549-Humans, pubmed-meshheading:17460549-Male, pubmed-meshheading:17460549-Middle Aged, pubmed-meshheading:17460549-Polymorphism, Genetic, pubmed-meshheading:17460549-RNA Splice Sites, pubmed-meshheading:17460549-Treatment Outcome
pubmed:year	2007
pubmed:articleTitle	A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression.
pubmed:affiliation	Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't