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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-1-14
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pubmed:abstractText |
To clarify the best cost-effective screening strategy for colorectal cancer in Japan, the cost-effectiveness ratio was compared among six currently performed procedures. The analysis was made using a simulation model to estimate long-term cost and effectiveness of the screening programs. In the screening by the immunological fecal occult blood test (FOBT), a comparison between the one- and two-day fecal collection methods indicated that the latter was more cost-effective than the former. A comparison was also made on the four workup methods: barium enema (BE) alone, a combination of BE and sigmoidoscopy (BE + SIG), total colonoscopy (TCF) alone, and a combination of BE and TCF (BE + TCF). The cost-effectiveness ratio was the lowest in the method using TCF alone, followed by those based on BE alone and BE + TCF, and the highest in the BE + SIG method. The superiority of TCF alone strategy was stable over a range of estimates such as the sensitivity of diagnostic tests, the probability of complications due to TCF, etc. It is concluded that a combination of the two-day FOBT and TCF yields the best cost-effectiveness.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0040-8727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-78
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1746016-Barium Sulfate,
pubmed-meshheading:1746016-Colonic Neoplasms,
pubmed-meshheading:1746016-Colonoscopy,
pubmed-meshheading:1746016-Cost-Benefit Analysis,
pubmed-meshheading:1746016-Enema,
pubmed-meshheading:1746016-Female,
pubmed-meshheading:1746016-Humans,
pubmed-meshheading:1746016-Japan,
pubmed-meshheading:1746016-Male,
pubmed-meshheading:1746016-Mass Screening,
pubmed-meshheading:1746016-Occult Blood,
pubmed-meshheading:1746016-Rectal Neoplasms,
pubmed-meshheading:1746016-Sigmoidoscopy,
pubmed-meshheading:1746016-Specimen Handling
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pubmed:year |
1991
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pubmed:articleTitle |
Cost-effectiveness analysis of screening for colorectal cancer in Japan.
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pubmed:affiliation |
Department of Public Health, Tohoku University School of Medicine, Sendai, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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