|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0011923,
umls-concept:C0016263,
umls-concept:C0016315,
umls-concept:C0026018,
umls-concept:C0068767,
umls-concept:C0383779,
umls-concept:C0449774,
umls-concept:C0966564,
umls-concept:C1261322,
umls-concept:C1280500,
umls-concept:C1516312,
umls-concept:C1883073
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|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2007-7-31
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|
pubmed:abstractText |
The 7-ketocholesterol (7KC)-induced cell death has some characteristics of apoptosis and is associated with polar lipid accumulation. So, we investigated the effects of the broad-spectrum caspase inhibitor z-VAD-fmk and of the caspase-2 inhibitor z-VDVAD-fmk on lipid profile evaluated by staining with Nile Red (NR).
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1552-4922
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2007 International Society for Analytical Cytology.
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|
pubmed:issnType |
Print
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|
pubmed:volume |
71
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
550-62
|
|
pubmed:meshHeading |
pubmed-meshheading:17458884-Amino Acid Chloromethyl Ketones,
pubmed-meshheading:17458884-Caspases,
pubmed-meshheading:17458884-Cell Nucleus,
pubmed-meshheading:17458884-Enzyme Inhibitors,
pubmed-meshheading:17458884-Factor Analysis, Statistical,
pubmed-meshheading:17458884-Flow Cytometry,
pubmed-meshheading:17458884-Fluorescence,
pubmed-meshheading:17458884-Humans,
pubmed-meshheading:17458884-Image Processing, Computer-Assisted,
pubmed-meshheading:17458884-Ketocholesterols,
pubmed-meshheading:17458884-Lipid Metabolism,
pubmed-meshheading:17458884-Microscopy,
pubmed-meshheading:17458884-Microscopy, Confocal,
pubmed-meshheading:17458884-Oxazines,
pubmed-meshheading:17458884-U937 Cells
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy.
|
|
pubmed:affiliation |
INSERM UMR 866 (Lipides, Nutrition et Cancer; équipe Biochimie Métabolique et Nutritionnelle), IFR Santé STIC, Université de Bourgogne-Faculté des Sciences Gabriel, 21000 Dijon, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
