Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-6-13
pubmed:abstractText
Extreme population differentiation, as measured by the F(ST) value, has been suggested as an indicator of recent population-specific positive selection. Elevated F(ST) values indicating high differentiation between continental groups were previously reported on a linkage disequilibrium region in the Neuregulin 1 gene, a gene which has been associated to schizophrenia. In the present study we show evidence that high F(ST) values may not necessarily imply the action of selection, in particular positive selection, neither globally nor regionally, using the example of the NRG1 gene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0340-6717
pubmed:author
pubmed:issnType
Print
pubmed:volume
121
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
759-62
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Extreme individual marker F(ST )values do not imply population-specific selection in humans: the NRG1 example.
pubmed:affiliation
Unitat de Biologia Evolutiva, Universitat Pompeu Fabra, Doctor Aiguader 88, Barcelona, 08003, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't