Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-4-25
pubmed:abstractText
Prostaglandins play a major role in inflammation and pain. They are synthesized by the two cyclooxygenase (COX) isoforms: COX-1, which is expressed constitutively in many cell types, and COX-2, which is induced at the site of inflammation. However, unlike peripheral tissues, COX-2 is expressed constitutively in the central nervous system and may play a role in nociceptive processes. The current study aimed to investigate the role of constitutive COX-2 in the spinal transmission of nociceptive signals in humans.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0003-3022
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1013-8
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Constitutive cyclooxygenase-2 is involved in central nociceptive processes in humans.
pubmed:affiliation
Institut National de la Santé et de la Recherche Médicale (INSERM) U-792, Centre Hospitalier Universitaire Ambroise Paré, Centre d'Evaluation et de Traitement de la Douleur, Assistance Publique - Hôpitaux de Paris (AP-HP), Boulogne-Billancourt, France.
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't