Source:http://linkedlifedata.com/resource/pubmed/id/17456980
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2007-4-25
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pubmed:abstractText |
Two new aminophenoxazinone compounds with antitumor activity, elloxazinone A and B, were isolated from the culture filtrate of Streptomyces griseus Acta 2871. Their chemical structures were determined by mass spectrometry, NMR spectroscopy and X-ray analysis. Elloxazinones A and B showed a moderate inhibition of the proliferation of human cells from gastric adenocarcinoma in vitro but a strong inhibition of hepatocellular carcinoma cells whereas elloxazinone B strongly inhibited the proliferation of human breast carcinoma cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
277-84
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pubmed:meshHeading |
pubmed-meshheading:17456980-Antibiotics, Antineoplastic,
pubmed-meshheading:17456980-Cell Cycle,
pubmed-meshheading:17456980-Cell Line, Tumor,
pubmed-meshheading:17456980-Fermentation,
pubmed-meshheading:17456980-Humans,
pubmed-meshheading:17456980-Magnetic Resonance Spectroscopy,
pubmed-meshheading:17456980-Oxazines,
pubmed-meshheading:17456980-Streptomyces griseus,
pubmed-meshheading:17456980-Structure-Activity Relationship
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pubmed:year |
2007
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pubmed:articleTitle |
Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871.
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pubmed:affiliation |
Institut für Chemie, Technische Universität Berlin.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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