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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-4-24
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pubmed:abstractText |
Aging is associated with an accumulation of cholesterol esters in the Bruch membrane. Cholesterol esters are prone to undergo oxidation and generate oxysterols that have cytotoxic and proinflammatory properties. We investigated the effects of three oxysterols on mitochondrial dysfunctions, inflammation, and oxidative stress in primary cultures of porcine retinal pigment epithelial (RPE) cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/24-hydroxycholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/25-hydroxycholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/7-ketocholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Fluoresceins,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxycholesterols,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Ketocholesterols,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/diacetyldichlorofluorescein
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0271-3683
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pubmed:author |
pubmed-author:AcarNiyaziN,
pubmed-author:BretillonLionelL,
pubmed-author:BronAlainA,
pubmed-author:ButeauBénédicteB,
pubmed-author:CabaretStéphanieS,
pubmed-author:Creuzot-GarcherCatherineC,
pubmed-author:JoffreCorinneC,
pubmed-author:LeclèreLaurentL,
pubmed-author:LizardGérardG,
pubmed-author:MalvitteLaureL,
pubmed-author:MartineLucyL
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
271-80
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pubmed:meshHeading |
pubmed-meshheading:17453947-Animals,
pubmed-meshheading:17453947-Chromatography, Gas,
pubmed-meshheading:17453947-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17453947-Fluoresceins,
pubmed-meshheading:17453947-Fluorescent Dyes,
pubmed-meshheading:17453947-Hydroxycholesterols,
pubmed-meshheading:17453947-Inflammation,
pubmed-meshheading:17453947-Interleukin-8,
pubmed-meshheading:17453947-Ketocholesterols,
pubmed-meshheading:17453947-Mitochondria,
pubmed-meshheading:17453947-Oxidative Stress,
pubmed-meshheading:17453947-Pigment Epithelium of Eye,
pubmed-meshheading:17453947-RNA, Messenger,
pubmed-meshheading:17453947-Reactive Oxygen Species,
pubmed-meshheading:17453947-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17453947-Swine
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pubmed:year |
2007
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pubmed:articleTitle |
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
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pubmed:affiliation |
Eye and Nutrition Research Group, INRA, UMR1129 FLAVIC, Dijon, France. cjoffre@dijon.inra.fr
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pubmed:publicationType |
Journal Article
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