Linked Life Data

17453440

Source:http://linkedlifedata.com/resource/pubmed/id/17453440

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
557
pubmed:dateCreated
2007-4-24
pubmed:abstractText
Sensorineural hearing loss is one of the most common disabilities in our society. Experimentally, many candidates for therapeutic molecules have been discovered. However, the lack of safe and effective methods for drug delivery to the cochlea has been a considerable obstacle to clinical application. Local application of therapeutic molecules into the cochlea has been used in clinic and in animal experiments. Advances in pharmacological technology provide various drug delivery systems via biomaterials, which can be utilized for local drug delivery to the cochlea. Recent studies in the field of otology have demonstrated the potential of synthetic and natural biomaterials for local drug delivery to the cochlea. Although problems still remain to be resolved for clinical application, introduction into clinical practice of these controlled-release systems may be reasonable because of their certain advantages over previous methods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0365-5237
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30-5
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Drug delivery systems for the treatment of sensorineural hearing loss.
pubmed:affiliation
Department of Otolaryngology-Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan. tnakagawa@ent.kuhp.kyoto-u.ac.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't