Source:http://linkedlifedata.com/resource/pubmed/id/17452048
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2007-5-7
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pubmed:abstractText |
Culture of bovine embryos in the presence of insulin-like growth factor-1 (IGF-1) can increase pregnancy rates following transfer to heat-stressed, lactating dairy cows. The objective of the present experiment was to determine whether the effect of IGF-1 on post-transfer embryo survival was a general effect or one specific to heat stress. Lactating recipients (n=311) were synchronized for timed-embryo transfer at four locations. Embryos were produced in vitro and cultured with or without 100 ng/mL IGF-1. At Day 7 after anticipated ovulation (Day 0), a single embryo was randomly transferred to each recipient. Pregnancy was diagnosed at Day 21 by elevated plasma progesterone concentrations, at Days 27-32 by ultrasonography, and at Days 41-49 by transrectal palpation. Transfers were categorized into two seasons, hot or cool (based on the month of transfer). There was a tendency (P<0.09) for an interaction between embryo treatment and season for pregnancy rate at Day 21; this interaction was significant at Days 30 and 45 (P<0.02). Recipients receiving IGF-1 treated embryos had higher pregnancy rates in the hot season but not in the cool season. There was a similar interaction between embryo treatment and season for overall calving rate (P<0.05). There was also an interaction between season and treatment affecting pregnancy loss between Days 21 and 30; recipients that received IGF-1 treated embryos had less pregnancy loss during this time period in the hot season but not in the cool season. The overall proportion of male calves born was 77.5%. In conclusion, treatment of embryos with IGF-1 improved pregnancy and calving rates following the transfer of in vitro produced embryos into lactating recipients, but only under heat-stress conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0093-691X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1518-29
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17452048-Abortion, Veterinary,
pubmed-meshheading:17452048-Animals,
pubmed-meshheading:17452048-Birth Weight,
pubmed-meshheading:17452048-Cattle,
pubmed-meshheading:17452048-Culture Media,
pubmed-meshheading:17452048-Embryo, Mammalian,
pubmed-meshheading:17452048-Embryo Culture Techniques,
pubmed-meshheading:17452048-Embryo Transfer,
pubmed-meshheading:17452048-Female,
pubmed-meshheading:17452048-Fertilization in Vitro,
pubmed-meshheading:17452048-Insulin-Like Growth Factor I,
pubmed-meshheading:17452048-Lactation,
pubmed-meshheading:17452048-Live Birth,
pubmed-meshheading:17452048-Male,
pubmed-meshheading:17452048-Pregnancy,
pubmed-meshheading:17452048-Pregnancy Rate,
pubmed-meshheading:17452048-Seasons,
pubmed-meshheading:17452048-Sex Ratio,
pubmed-meshheading:17452048-Temperature,
pubmed-meshheading:17452048-Time Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Interaction between season and culture with insulin-like growth factor-1 on survival of in vitro produced embryos following transfer to lactating dairy cows.
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pubmed:affiliation |
Department of Animal Sciences, University of Florida, Gainesville, FL 32611-0910, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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