rdf:type |
|
lifeskim:mentions |
umls-concept:C0015127,
umls-concept:C0016411,
umls-concept:C0017262,
umls-concept:C0018798,
umls-concept:C0025677,
umls-concept:C0043457,
umls-concept:C0185117,
umls-concept:C1314792,
umls-concept:C1412805,
umls-concept:C1415475,
umls-concept:C1527148,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
2007-4-23
|
pubmed:abstractText |
To study the effect of methotrexate (MTX), a folic acid antagonist which can lead to folic acid deficient, on the cardiac development and on the expressions of BMP2b and HAS2 in zebrafish.
|
pubmed:language |
chi
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1008-8830
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
159-63
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17448316-Abnormalities, Drug-Induced,
pubmed-meshheading:17448316-Animals,
pubmed-meshheading:17448316-Bone Morphogenetic Protein 2,
pubmed-meshheading:17448316-Bone Morphogenetic Proteins,
pubmed-meshheading:17448316-Down-Regulation,
pubmed-meshheading:17448316-Folic Acid Antagonists,
pubmed-meshheading:17448316-Gene Expression Regulation,
pubmed-meshheading:17448316-Glucuronosyltransferase,
pubmed-meshheading:17448316-Heart Defects, Congenital,
pubmed-meshheading:17448316-Methotrexate,
pubmed-meshheading:17448316-Polymerase Chain Reaction,
pubmed-meshheading:17448316-Zebrafish,
pubmed-meshheading:17448316-Zebrafish Proteins
|
pubmed:year |
2007
|
pubmed:articleTitle |
[Folic acid antagonist methotrexate causes the development malformation of heart and down-regulates the BMP2b and HAS2 expressions in zebrafish].
|
pubmed:affiliation |
Children's Hospital of Fudan University, Shanghai, China.
|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|