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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-5-24
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pubmed:abstractText |
We have previously reported that human paraoxonase 3 (PON3) is an HDL-associated protein capable of preventing LDL oxidation in vitro. The objective of the present study was to determine whether elevated levels of human PON3 in mice could protect against the progression of atherosclerosis in vivo.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Aryldialkylphosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Esterases,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Peroxides,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/PON3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1368-74
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17446441-Adenoviridae,
pubmed-meshheading:17446441-Animals,
pubmed-meshheading:17446441-Apolipoproteins E,
pubmed-meshheading:17446441-Aryldialkylphosphatase,
pubmed-meshheading:17446441-Atherosclerosis,
pubmed-meshheading:17446441-Cells, Cultured,
pubmed-meshheading:17446441-Chemotaxis,
pubmed-meshheading:17446441-Cholesterol,
pubmed-meshheading:17446441-Dietary Fats,
pubmed-meshheading:17446441-Disease Models, Animal,
pubmed-meshheading:17446441-Disease Progression,
pubmed-meshheading:17446441-Esterases,
pubmed-meshheading:17446441-Female,
pubmed-meshheading:17446441-Gene Therapy,
pubmed-meshheading:17446441-Gene Transfer Techniques,
pubmed-meshheading:17446441-Genetic Vectors,
pubmed-meshheading:17446441-Humans,
pubmed-meshheading:17446441-Lipid Peroxides,
pubmed-meshheading:17446441-Lipoproteins, HDL,
pubmed-meshheading:17446441-Lipoproteins, LDL,
pubmed-meshheading:17446441-Liver,
pubmed-meshheading:17446441-Macrophages,
pubmed-meshheading:17446441-Mice,
pubmed-meshheading:17446441-Mice, Knockout,
pubmed-meshheading:17446441-Monocytes,
pubmed-meshheading:17446441-Time Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice.
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pubmed:affiliation |
Atherosclerosis Research Unit, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90095, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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