Linked Life Data

17442290

Source:http://linkedlifedata.com/resource/pubmed/id/17442290

Statements in which the resource exists.
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pubmed-article:17442290pubmed:abstractTextTwo separate and complementary assays, total mitochondrial fatty acid beta-oxidation (FAO) flux rate and acylcarnitine profiling, have been used to establish a definitive diagnosis of FAO defects (FAOD) in cultured cells. We developed a novel functional assay for total FAO rate assay by measurement of deuterated water enrichment and to combine it with the conventional acylcarnitine profiling method into a single tracer incubation experiment.lld:pubmed
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pubmed-article:17442290pubmed:articleTitleA novel functional assay for simultaneous determination of total fatty acid beta-oxidation flux and acylcarnitine profiling in human skin fibroblasts using (2)H(31)-palmitate by isotope ratio mass spectrometry and electrospray tandem mass spectrometry.lld:pubmed
pubmed-article:17442290pubmed:affiliationDepartment of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT Hong Kong SAR.lld:pubmed
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pubmed-article:17442290pubmed:publicationTypeValidation Studieslld:pubmed