Linked Life Data

17441043

Source:http://linkedlifedata.com/resource/pubmed/id/17441043

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2007-4-18
pubmed:abstractText
A series of supramolecular complexes between a water-soluble achiral polythiophene derivative (PT-1) and various nucleotides has been prepared. It was found that upon the introduction of adenosine diphosphate (ADP), adenosine triphosphate (ATP), and uridine triphosphate (UTP) into aqueous solutions of achiral PT-1, which has a random-coiled conformation, chiral supramolecular pi-stacked aggregates of PT-1 can be constructed. These complexes exhibit an unique split-type induced circular dichroism (ICD) in the pi-pi* transition region of the main chain. In particular, it was found that the Cotton effect of the chiral supramolecular PT-1/ATP aggregates reveals a dramatic inversion of chirality with a change in the concentration of ATP, which has not been previously observed in chiral macromolecular complexes. On the basis of extensive investigations performed with UV/Vis spectroscopy, CD spectroscopy, TEM, AFM, and dynamic light scattering (DLS), a possible mechanism for the formation of chiral superstructures of PT-1 and chiroptical inversion induced by changes in ATP concentration is proposed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1861-471X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
95-101
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Unexpected chiroptical inversion observed for supramolecular complexes formed between an achiral polythiophene and ATP.
pubmed:affiliation
Department of Chemistry and Biochemistry, Graduated School of Engineering, Kyushu University, Fukuoka 819-0395, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't