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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-4-25
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pubmed:abstractText |
Neuromyelitis optica (NMO) is a demyelinating disease of the central nervous system (CNS) of putative autoimmune aetiology. Early discrimination between multiple sclerosis (MS) and NMO is important, as optimum treatment for both diseases may differ considerably. Recently, using indirect immunofluorescence analysis, a new serum autoantibody (NMO-IgG) has been detected in NMO patients. The binding sites of this autoantibody were reported to colocalize with aquaporin 4 (AQP4) water channels. Thus we hypothesized that AQP4 antibodies in fact characterize NMO patients.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-10496275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-11456302,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-11997067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-12076996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-12524556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-12629245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-15589308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-16087714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-16453327,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-16709582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-16717206,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-8774400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17439296-9894896
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1549-1676
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pubmed:author |
pubmed-author:AktasOrhanO,
pubmed-author:AppelhansHeribertH,
pubmed-author:BauerOliverO,
pubmed-author:BergamaschiRobertoR,
pubmed-author:BluthnerMartinM,
pubmed-author:FranciottaDiegoD,
pubmed-author:HohlfeldReinhardR,
pubmed-author:JariusSvenS,
pubmed-author:LittletonEdwardE,
pubmed-author:PalaceJacquelineJ,
pubmed-author:PaulFriedemannF,
pubmed-author:SeeligHans-PeterHP,
pubmed-author:VincentAngelaA,
pubmed-author:ZippFraukeF
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e133
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17439296-Adolescent,
pubmed-meshheading:17439296-Adult,
pubmed-meshheading:17439296-Aged,
pubmed-meshheading:17439296-Aged, 80 and over,
pubmed-meshheading:17439296-Aquaporin 4,
pubmed-meshheading:17439296-Autoantibodies,
pubmed-meshheading:17439296-Child,
pubmed-meshheading:17439296-Diagnosis, Differential,
pubmed-meshheading:17439296-Female,
pubmed-meshheading:17439296-Humans,
pubmed-meshheading:17439296-Male,
pubmed-meshheading:17439296-Middle Aged,
pubmed-meshheading:17439296-Multiple Sclerosis,
pubmed-meshheading:17439296-Neuromyelitis Optica,
pubmed-meshheading:17439296-Radioimmunoprecipitation Assay,
pubmed-meshheading:17439296-Recombinant Proteins,
pubmed-meshheading:17439296-Sensitivity and Specificity
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pubmed:year |
2007
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pubmed:articleTitle |
Antibody to aquaporin 4 in the diagnosis of neuromyelitis optica.
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pubmed:affiliation |
Cecilie-Vogt-Clinic for Molecular Neurology, Charité, University Medicine Berlin, Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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