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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-4-17
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pubmed:abstractText |
Cryptorchidism affects 1% to 9% of full-term male neonates. Hypospadias is the second most frequent congenital anomaly seen in newborn males. These pathological conditions are part of the testicular dysgenesis syndrome. Insulin-like factor 3 and LGR8 (leucine-rich repeat-containing G protein-coupled receptor 8), acting as a hormone and a receptor, respectively, are involved in control of the first phase of testicular descent via gubernacular development.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-5347
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pubmed:author |
pubmed-author:AgoulnikAlexander IAI,
pubmed-author:BarakatAbdelhamidA,
pubmed-author:BogatchevaNatalia VNV,
pubmed-author:ChadliEl Bekkayel B,
pubmed-author:ChafikAbdelazizA,
pubmed-author:El HouateBrahimB,
pubmed-author:FengShuS,
pubmed-author:ImkenLailaL,
pubmed-author:McElreaveyKenK,
pubmed-author:RoubaHassanH,
pubmed-author:SibaiHichamH
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pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1947-51
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17437853-Abnormalities, Multiple,
pubmed-meshheading:17437853-Child,
pubmed-meshheading:17437853-Cryptorchidism,
pubmed-meshheading:17437853-DNA,
pubmed-meshheading:17437853-Gene Expression,
pubmed-meshheading:17437853-Genetic Predisposition to Disease,
pubmed-meshheading:17437853-Humans,
pubmed-meshheading:17437853-Hypospadias,
pubmed-meshheading:17437853-Insulin,
pubmed-meshheading:17437853-Male,
pubmed-meshheading:17437853-Mutation,
pubmed-meshheading:17437853-Open Reading Frames,
pubmed-meshheading:17437853-Penis,
pubmed-meshheading:17437853-Polymerase Chain Reaction,
pubmed-meshheading:17437853-Polymorphism, Genetic,
pubmed-meshheading:17437853-Promoter Regions, Genetic,
pubmed-meshheading:17437853-Proteins,
pubmed-meshheading:17437853-Receptors, G-Protein-Coupled
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pubmed:year |
2007
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pubmed:articleTitle |
Novel mutations involving the INSL3 gene associated with cryptorchidism.
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pubmed:affiliation |
Human Genetics Department, Institut Pasteur of Morocco, Casablanca, Morocco.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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